What is the role of CT scanning and MRI in the workup of primary hyperparathyroidism?

Updated: Oct 02, 2018
  • Author: Lawrence Kim, MD, FACS, FACE; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Answer

CT scanning and magnetic resonance imaging (MRI) have also been used also to locate abnormal parathyroid glands. Standard CT scanning has inadequate sensitivity. Newer techniques of CT scanning with dynamic contrast images (4D-CT) have shown promise, with accuracy rates as high as 88%. [13, 14]  (A study by Ramirez et al suggested that two-phase CT scanning is as effective as the four-dimensional modality in localization of the parathyroids, including in cases of small adenomas, reoperation, and multiglandular disease, with less radiation exposure for the patient. [15] ) MRI can be useful, particularly in cases of recurrent or persistent disease and in ectopic locations such as the mediastinum.


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