Why should McCune-Albright syndrome (MAS) be considered in patients with recurrent fractures?

Updated: Jan 17, 2019
  • Author: Gabriel I Uwaifo, MD; Chief Editor: George T Griffing, MD  more...
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Answer

Early recognition of McCune-Albright syndrome (MAS) is vital. The diagnostic possibility of MAS should be considered in all patients with recurrent fractures, particularly if the fractures occur in the setting of minimal trauma or without trauma. The common pitfall is to simply refer the patient for orthopedic procedures whenever a fracture occurs, without considering the underlying primary diagnosis. The physician should have a high index of suspicion for other endocrinopathies associated with the condition.


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