What are histologic findings of adrenal carcinoma in the workup of primary aldosteronism?

Updated: Mar 24, 2020
  • Author: Gabriel I Uwaifo, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Answer

Primary aldosteronism syndrome rarely occurs in the setting of adrenal carcinoma, whereby the cause of the hypersecretion of aldosterone is a malignancy (rather than a benign adenoma). In such cases, histopathology reveals the typical features of adrenocortical carcinoma (ACC), including mitotic figures, local invasion, and locoregional lymph node metastases.


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