What is the diagnostic value of the aldosterone-to-cortisol ratios in the workup of primary aldosteronism?

Updated: Mar 24, 2020
  • Author: Gabriel I Uwaifo, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Answer

Most patients with a unilateral source of aldosterone have adrenal-to-adrenal aldosterone-to-cortisol ratios of greater than 4. Ratios of less than 3 suggest hyperplasia, and values of 3-4 are considered indeterminate results.


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