How does aging affect growth hormone (GH) secretion?

Updated: Apr 14, 2020
  • Author: Angela Gentili, MD; Chief Editor: George T Griffing, MD  more...
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Answer

Incidence is unknown because somatopause may be part of normal aging rather than a disease. In aging men, GH secretion declines by 50% every 7 years after age 18-25 years. In men 60 years or older, 35% are GH-deficient. Serum IGF-1 levels also decline with 85% of healthy men older than 59 years demonstrating low serum IGF-1 levels below the 2.5th percentile for younger men. [1]


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