What are the criteria for deep venous thrombosis (DVT) prophylaxis prior to orthopedic surgery?

Updated: Jul 25, 2019
  • Author: David A Forsh, MD; Chief Editor: Vinod K Panchbhavi, MD, FACS  more...
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Answer

Answer

An ideal anticoagulant should be easy to administer (preferably oral), should be effective and safe with a minimum of possible complications or adverse effects, have a rapid onset, have a therapeutic half-life, and require minimal or no monitoring. The action of the anticoagulant should be predictable with few drug or dietary interactions, and it should be reversible. The drug should also be inexpensive. Unfortunately, these criteria are often difficult to achieve. Several anticoagulant agents exist today, and each of them incorporates some of these characteristics, but no single agent combines all these attributes.


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