Which factor Xa and direct thrombin inhibitors are used in the treatment of venous thromboembolism (VTE)?

Updated: Nov 05, 2020
  • Author: Vera A De Palo, MD, MBA, FCCP; Chief Editor: Vinod K Panchbhavi, MD, FACS  more...
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Answer

Apixaban, dabigatran, rivaroxaban, edoxaban, and betrixaban are alternatives to warfarin for prophylaxis or treatment of DVT and PE. Apixaban, edoxaban, rivaroxaban, and betrixaban all inhibit factor Xa, whereas dabigatran is a direct thrombin inhibitor.


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