Which factor Xa and direct thrombin inhibitors are used in the treatment of venous thromboembolism (VTE)?

Updated: Nov 05, 2020
  • Author: Vera A De Palo, MD, MBA, FCCP; Chief Editor: Vinod K Panchbhavi, MD, FACS, FAOA, FABOS, FAAOS  more...
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Apixaban, dabigatran, rivaroxaban, edoxaban, and betrixaban are alternatives to warfarin for prophylaxis or treatment of DVT and PE. Apixaban, edoxaban, rivaroxaban, and betrixaban all inhibit factor Xa, whereas dabigatran is a direct thrombin inhibitor.

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