How is venous thromboembolism (VTE) treated during pregnancy?

Updated: Nov 05, 2020
  • Author: Vera A De Palo, MD, MBA, FCCP; Chief Editor: Vinod K Panchbhavi, MD, FACS, FAOA, FABOS, FAAOS  more...
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In pregnancy, establishing a clear guideline for the treatment of thromboembolic disease is difficult from an evidence-based perspective. Heparin is the anticoagulant of choice, given its relative safety for the fetus.

Heparin therapy should be discontinued immediately before delivery, and then both heparin and warfarin therapy can be started post partum.

Pregnant women with a history of previous thromboembolic disease probably should receive some prophylaxis, as the estimated range of recurrence is 0-15%.

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