Does the prevalence of dysbetalipoproteinemia vary among racial groups?

Updated: Dec 19, 2019
  • Author: Mary Ellen T Sweeney, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Answer

As noted above, although the frequency of apo E2 varies somewhat by race, the prevalence of dysbetalipoproteinemia appears to be similar among races. The racial differences are a consequence not only of apo E2 frequency but also of the prevalence of the metabolic abnormalities necessary to cause dysbetalipoproteinemia.

Nonhispanic blacks often have lower triglyceride levels, possibly related to an increase in LPL activity. [26] Racial predisposition has not been described for lipoprotein lipase deficiency or apo CII deficiency.


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