Which physical findings suggest hypertriglyceridemia (high triglyceride levels)?

Updated: Dec 19, 2019
  • Author: Mary Ellen T Sweeney, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Answer

On examination, findings may be normal, or they may include the following:

  • GI: Tenderness to palpation over mid-epigastric or upper right/left quadrants; hepatomegaly

  • Dermatologic: Eruptive xanthomas on back (see the image below), buttocks, chest, proximal extremities; palmar xanthomas in dysbetalipoproteinemia

    Eruptive xanthomas on the back of a patient admitt Eruptive xanthomas on the back of a patient admitted with a triglyceride level of 4600 mg/dL and acute pancreatitis.
  • Cardiovascular: Decreased pedal pulses or ankle/brachial index in presence of peripheral vascular disease

  • Ophthalmologic: Corneal arcus, lipemia retinalis, xanthelasmas [2]

  • Neurologic: Memory loss, dementia, and depression in the presence of chylomicronemia syndrome


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