Which physical findings are characteristic of type III spinal muscle atrophy (SMA)?

Updated: May 04, 2020
  • Author: Ashish S Ranade, MBBS, MS, MRCS; Chief Editor: Jeffrey A Goldstein, MD  more...
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Patients with type III SMA are able to walk independently early in life and maintain their ambulatory capacity into adolescence. They may have difficulty with coughing and swallowing with nocturnal hypoventilation.They develop muscle weakness, aching, and joint overuse symptoms. Weakness may cause foot drop, and patients have limited endurance. A third of the patients become wheelchair-bound as adults (mean age, 40 years).

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