Which histologic findings are characteristic of diffuse idiopathic skeletal hyperostosis (DISH)?

Updated: Oct 23, 2018
  • Author: Bruce M Rothschild, MD; Chief Editor: Jeffrey D Thomson, MD  more...
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Answer

Histologic examination of vertebral specimens from patients with diffuse idiopathic skeletal hyperostosis (DISH) show partial or complete bone bridges consisting of cortical haversian bone, accompanied by morphological changes in the adjoining part of the intervertebral disc. [37] Ossified tissues in DISH are composed of normal-appearing haversian bone, as opposed to the wormian or disorganized structure of bone seen in patients with hypervitaminosis A. [38]


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