What is included in inpatient care for osteosarcoma?

Updated: Dec 04, 2018
  • Author: Charles T Mehlman, DO, MPH; Chief Editor: Omohodion (Odion) Binitie, MD  more...
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Answer

Further cycles of chemotherapy generally necessitate inpatient admission for administration and monitoring. Active drugs include methotrexate, cisplatin and doxorubicin. Patients treated with high-dose alkylating agents are at higher risk for myelodysplasia and leukemia. Therefore, a complete blood count (CBC) should be performed periodically.

Patients with fever and neutropenia should be admitted for IV antibiotic therapy and monitoring.

Admission is required perioperatively for local control (surgical resection, amputation), usually around week 10 of therapy. Resection of metastatic disease (eg, lung nodules) is typically performed at the end of therapy.

Patients may require admission for a multitude of other medical problems during their chemotherapy treatment phase, including, but not limited to, varicella infection (for IV acyclovir and monitoring), mucositis (for narcotics), dehydration, meningitis, constipation, fungal pneumonia, and cystitis.


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