How is osteosarcoma staged?

Updated: Jul 01, 2020
  • Author: Charles T Mehlman, DO, MPH; Chief Editor: Omohodion (Odion) Binitie, MD  more...
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The purpose of staging tumors is to stratify risk groups. The conventional staging used for other solid tumors is not appropriate for skeletal tumors, because these tumors rarely involve lymph nodes or regional spread.

Instead, the staging system introduced by Enneking in 1980 is based on histologic grade (low vs high), anatomic location (intracompartmental vs extracompartmental), and presence or absence of metastases. [25, 26] This system (also referred to as the staging system of the Musculoskeletal Tumor Society [MSTS]) applies to all musculoskeletal tumors (both bone and soft tissue). It has been credited with bringing order to the surgical treatment of a group of tumors for which treatment was previously approached rather haphazardly.

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