How are soft-tissue tumors treated?

Updated: Dec 03, 2018
  • Author: Vinod B Shidham, MD, FRCPath; Chief Editor: Omohodion (Odion) Binitie, MD  more...
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Management of soft-tissue tumors may evolve as a result of the advent of molecular diagnostics and antitumor therapies. It is problematic, however, that despite the existence of many histologic subtypes of soft-tissue tumors, only a small number of them are seen at any one institution. More multi-institutional studies are necessary.

Soft-tissue sarcomas are challenging lesions that demand a multidisciplinary and multimodality approach for proper clinical evaluation and treatment. Although in the past, high-grade extremity sarcomas were treated with amputation, limb-sparing therapies for these tumors are well established today. Successful management of such lesions requires a multidisciplinary team of surgeons, radiologists, pathologists, medical oncologists, radiation oncologists, oncology nurses, rehabilitation therapists, and social workers.

Because of the comparative rarity of soft-tissue sarcomas and a general lack of related medical expertise, patients with these tumors should be considered for referral, preferably during the initial evaluation phase, to medical centers experienced in sarcoma management. [36]

For more information on treatment of these sarcomas, see Soft-Tissue Sarcoma Guidelines and Soft-Tissue Sarcoma Treatment Protocols.

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