What is the role of biopsy in the workup of soft-tissue tumors?

Updated: Dec 03, 2018
  • Author: Vinod B Shidham, MD, FRCPath; Chief Editor: Omohodion (Odion) Binitie, MD  more...
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Biopsy usually is indicated for a soft-tissue mass arising in a patient without a history of trauma or for a mass that persists for more than 6 weeks after local trauma. All soft-tissue masses larger than 5 cm, as well as any enlarging or symptomatic lesions, also should be biopsied. Small, subcutaneous lesions that persist unchanged for years may be considered for observation rather than biopsy. A high level of suspicion is necessary to ensure early treatment.

Early tissue diagnosis is the most important component of multimodality treatment for soft-tissue tumor. Proper and timely biopsy is critical. An inadequately performed biopsy may complicate patient care and result in loss of limb or life.

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