Which medications in the drug class Corticosteroids are used in the treatment of Trigger Finger?

Updated: Apr 26, 2021
  • Author: Satishchandra Kale, MD, MBBS, MBA, MCh(Orth), FRCS(Edin), FRCS(Tr&Orth); Chief Editor: Harris Gellman, MD  more...
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Answer

Corticosteroids

In contrast to the widespread systemic distribution that occurs when an oral anti-inflammatory drug is administered, a local corticosteroid injection can achieve the focal placement of a potent anti-inflammatory agent at the site of maximal tenderness or inflammation. A variety of corticosteroid preparations are available. Commonly, the corticosteroid is mixed with a local anesthetic agent prior to injection. The clinician has numerous local anesthetic agents from which to choose.

Methylprednisolone (A-Methapred, Depo-Medrol, Solu-Medrol, Medrol)

Corticosteroids are commonly used in local injections administered to bursae or joints. The drugs provide a local anti-inflammatory effect while minimizing some of the gastrointestinal and other risks of systemic medications.

Dexamethasone acetate (Baycadron)

This agent decreases inflammation by suppressing the migration of polymorphonuclear leukocytes and reducing capillary permeability. The dosage varies with the degree of inflammation and the size of the affected area.

Hydrocortisone acetate (Solu-Cortef, Cortef, A-Hydrocort)

Hydrocortisone acetate decreases inflammation by suppressing the migration of polymorphonuclear leukocytes and reversing increased capillary permeability. The dosage varies with the degree of inflammation and the size of the affected area.

Betamethasone (Celestone, Celestone Soluspan)

Betamethasone is the drug of choice for intra-articular injections. It does not crystallize if used with paraben-free anesthetic preparations.

Triamcinolone (Aristospan, Kenalog-10, Kenalog-40)

Triamcinolone is used for inflammatory conditions responsive to steroids; it decreases inflammation by suppressing the migration of polymorphonuclear leukocytes and reversing capillary permeability. This is the preferred drug, owing to its longer duration of action.


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