What is the efficacy of scintigraphy for the diagnosis of pheochromocytoma?

Updated: Aug 10, 2018
  • Author: Michael A Blake, MBBCh, MRCPI, FRCR; Chief Editor: George T Griffing, MD  more...
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Answer

Estimates of the sensitivity and specificity of 123I-MIBG vary widely. Reported sensitivity ranges from 53-94% and specificity ranges from 82-92%. [49, 50, 51]  123I has a short half-life and is expensive.

A somatostatin receptor analog, indium-111 (111In) pentetreotide, is less sensitive than MIBG. However, it may be used to visualize pheochromocytomas that do not concentrate MIBG.


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