Which patients should be screened for pheochromocytoma and what test should be used?

Updated: Jul 20, 2020
  • Author: Michael A Blake, MBBCh, MRCPI, FRCR; Chief Editor: George T Griffing, MD  more...
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Answer

High-risk patients, including those who have a genetic syndrome that predisposes them to pheochromocytoma (eg, multiple endocrine neoplasia [MEN] types 2A or 2B, von Hippel-Lindau [VHL] disease, neurofibromatosis, a prior history of a pheochromocytoma, a family history of a pheochromocytoma), should be screened with plasma metanephrine testing. In these scenarios, a higher-sensitivity test that lacks specificity is justified. [40]


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