What are Endocrine Society, the American Association for Clinical Chemistry, and the European Society of Endocrinology joint diagnostic guidelines for pheochromocytoma?

Updated: Aug 10, 2018
  • Author: Michael A Blake, MBBCh, MRCPI, FRCR; Chief Editor: George T Griffing, MD  more...
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Answer

The Endocrine Society, the American Association for Clinical Chemistry, and the European Society of Endocrinology have released clinical practice guidelines for the diagnosis and management of pheochromocytoma and paraganglioma (jointly referred to as PPGL). [32, 33]

  • Biochemical testing via measurement of plasma free metanephrines [34] or urinary fractionated metanephrines should be performed in patients suspected of having PPGL.
  • Patients with a known germ-line mutation that predisposes to PPGL should undergo periodic biochemical testing.
  • Computed tomography (CT), rather than magnetic resonance imaging (MRI), is recommended as the first-line imaging technique.
  • Blood pressure, heart rate, and glucose levels should be monitored immediately after surgery.
  • Patients with PPGLs should participate in shared decision-making for genetic testing.

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