What is the inheritance pattern for succinate dehydrogenase complex?

Updated: Aug 10, 2018
  • Author: Michael A Blake, MBBCh, MRCPI, FRCR; Chief Editor: George T Griffing, MD  more...
  • Print
Answer

The succinate dehydrogenase subunit C protein is encoded by the SDHC gene, and mutations are known to cause paraganglioma. One family with a mutation in this gene showed maternal inheritance of the condition, [17] but subsequent investigation has suggested an autosomal dominant inheritance pattern without evidence of imprinting.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!