How is multiple endocrine neoplasia type 2A (MEN 2A) diagnosed and what is the risk of developing pheochromocytomas?

Updated: Aug 10, 2018
  • Author: Michael A Blake, MBBCh, MRCPI, FRCR; Chief Editor: George T Griffing, MD  more...
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Answer

Clinical diagnosis of MEN 2A requires the occurrence of 2 or more endocrine tumors in one individual or in close relatives. The risk for medullary thyroid carcinoma is 95%, the risk for pheochromocytoma is 50%, and the risk for parathyroid disease is between 20% and 30%. [12]


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