What is preoperative medical stabilization for pheochromocytoma?

Updated: Aug 10, 2018
  • Author: Michael A Blake, MBBCh, MRCPI, FRCR; Chief Editor: George T Griffing, MD  more...
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Preoperative medical stabilization is provided as follows:

  • Start alpha blockade with phenoxybenzamine 7-10 days preoperatively
  • Provide volume expansion with isotonic sodium chloride solution
  • Encourage liberal salt intake
  • Initiate a beta blocker only after adequate alpha blockade, to avoid precipitating a hypertensive crisis from unopposed alpha stimulation
  • Administer the last doses of oral alpha and beta blockers on the morning of surgery

See Treatment and Medication for more detail.

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