How is liothyronine used for the treatment of myxedema coma (crisis)?

Updated: Aug 31, 2020
  • Author: Mohsen S Eledrisi, MD, FACP, FACE; Chief Editor: George T Griffing, MD  more...
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Liothyronine (T3) has a short half-life and must be administered every 8 hours. Because of concerns about abrupt onset and fluctuating concentrations in tissues, coadministration of T3 with T4 is recommended. 

Oral levothyroxine is taken daily 30-60 minutes before breakfast.

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