How are thyroid hormones used for the treatment of myxedema coma (crisis)?

Updated: Aug 31, 2020
  • Author: Mohsen S Eledrisi, MD, FACP, FACE; Chief Editor: George T Griffing, MD  more...
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IV dosage form has a long half-life, so it can be administered once-daily and is the preferred route of administration in patients with myxedema coma because gastrointestinal tract absorption may be compromised. It is preferred by many authorities given its slow onset of action and sustained effect, making adverse effects less likely to occur and serum levels easier to monitor. Lower doses are recommended for patients who have arrhythmias or coronary artery disease.

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