What is the role of lab testing in the workup of plantar heel pain?

Updated: Feb 10, 2020
  • Author: Vinod K Panchbhavi, MD, FACS; Chief Editor: Thomas M DeBerardino, MD  more...
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Generally, plantar fasciitis is a clinical diagnosis; laboratory and imaging studies are rarely indicated. However, heel pain, especially when it is bilateral, can be a rare primary presenting sign of systemic inflammatory disorders. If a patient presents with bilateral heel pain in association with systemic symptoms, the blood should be screened for inflammatory markers, such as the erythrocyte sedimentation rate (ESR), human leukocyte antigen (HLA)-B27, rheumatoid factor (RF), and antinuclear antibodies (ANA).

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