What is the efficacy of radiation therapy for the treatment for pituitary macroadenomas?

Updated: Mar 23, 2018
  • Author: James R Mulinda, MD, FACP; Chief Editor: George T Griffing, MD  more...
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Answer

Recent studies show the benefits of radiation. [7] Radiosurgery using a gamma knife employs a computer-assisted stereotactic mapping followed by several discrete radiation treatment fields to the tumor. This allows targeting maximal radiation to the tumor while minimizing radiation to the surrounding tissues. Incidence of hypopituitarism is less.

Advances with gamma radiation are associated with a very low incidence of postradiation hypopituitarism if the radiation dose is kept at less than 15 Gy. [8]


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