What causes pituitary macroadenomas?

Updated: Mar 23, 2018
  • Author: James R Mulinda, MD, FACP; Chief Editor: George T Griffing, MD  more...
  • Print
Answer

The cause of pituitary macroadenomas is unknown. The most favored theory attributes monoclonal neoplastic transformation of pituitary cells as the cause of tumor initiation and growth. The monoclonal nature of most pituitary tumors and their retention of a response to negative feedback by hormones produced by target organs support this hypothesis.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!