How is cardiovascular risk assessed in the workup of insulin resistance?

Updated: Aug 07, 2019
  • Author: Samuel T Olatunbosun, MD, FACP, FACE; Chief Editor: George T Griffing, MD  more...
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Other cardiac tests include echocardiography and stress testing, depending on the presentation.

A risk-assessment calculator, based on data from the Framingham Heart Study for estimating 10-year cardiovascular risk, is available. This calculator estimates the 10-year risk for hard coronary heart disease outcomes (myocardial infarction and coronary death). The tool is designed to estimate risk in adults aged 20 years and older who do not have heart disease or diabetes. The ACC/AHA Pooled Cohort Equations CV Risk Calculator was developed as a 10-year risk assessment tool for atherosclerotic cardiovascular disease from multiple community-based cohorts (including the Framingham Heart study). [63]

For patients with insulin resistance without overt diabetes, the metabolic syndrome criteria for cardiovascular risk stratification are less sensitive than those of the Framingham Risk Score, which takes into account age, total cholesterol, tobacco use, HDL-C, and blood pressure, but not diabetes.

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