What is the role of thyroid hormone replacement in hypothyroidism and adrenal crisis?

Updated: Mar 03, 2021
  • Author: Philip R Orlander, MD, FACP; Chief Editor: George T Griffing, MD  more...
  • Print
Answer

Thyroid hormone replacement can precipitate adrenal crises in patients with untreated adrenal insufficiency by enhancing hepatic corticosteroid metabolism. If adrenal insufficiency is suspected, it should be confirmed or ruled out; if confirmed, it should be treated before treatment of hypothyroidism.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!