How is myxedema coma treated?

Updated: Mar 03, 2021
  • Author: Philip R Orlander, MD, FACP; Chief Editor: George T Griffing, MD  more...
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Treatment of myxedema coma is as follows:

  • Intravenous (IV) LT4 at a dose of 4 µg/kg of lean body weight, or approximately 200-250 µg, as a bolus in a single or divided dose, depending on the patient’s risk of cardiac disease

  • After 24 hours, 100 µg LT4 IV, then 50 µg/day IV

  • Stress doses of IV glucocorticoids

  • Subsequent adjustment of the LT4 dose can be based on clinical and laboratory findings

See Treatment and Medication for more detail.

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