What are the symptoms and signs of levothyroxine (LT4) overtreatment in hypothyroidism?

Updated: Mar 03, 2021
  • Author: Philip R Orlander, MD, FACP; Chief Editor: George T Griffing, MD  more...
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After dose stabilization, patients can be monitored with annual clinical evaluations and TSH monitoring. Patients should be monitored for symptoms and signs of overtreatment, which include the following:

  • Tachycardia

  • Palpitations

  • Atrial fibrillation

  • Nervousness

  • Tiredness

  • Headache

  • Increased excitability

  • Sleeplessness

  • Tremors

  • Possible angina

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