What is the role of imaging studies in the workup of central retinal vein occlusion (CRVO)?

Updated: Apr 18, 2019
  • Author: Lakshmana M Kooragayala, MD; Chief Editor: Douglas R Lazzaro, MD, FAAO, FACS  more...
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Answer

Color Doppler imaging is a noninvasive quantitative method of assessing the retrobulbar circulation. Detection of low venous velocities has been used to predict the onset of iris neovascularization. At present, this is performed as an investigational procedure in large facilities. [17]

Optical coherence tomography (OCT) [18] scanning is a noninvasive, noncontact, transpupillary imaging technology that can image retinal structures in vivo with an axial resolution of 1-15 µm. Spectral-domain OCT is used to detect intraretinal and subretinal fluid and to measure the thickness of individual retinal layers. OCT provides information regarding the health of photoreceptors and ganglion cell layers. OCT is used exclusively to monitor macular edema over time and the response with various treatment modalities. [18, 19]

In addition to providing quantitative measurements of central retinal thickness, spectral-domain OCT reveals disorganization of the retinal inner layers (DRIL) and ellipsoid zone disruptions, which are used increasingly as biomarkers for assessing visual outcomes to various therapeutic agents. [20]


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