Which conditions are associated with central retinal vein occlusion (CRVO)?

Updated: Apr 18, 2019
  • Author: Lakshmana M Kooragayala, MD; Chief Editor: Douglas R Lazzaro, MD, FAAO, FACS  more...
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Some of the conditions in which CRVO has been associated include the following:

  • Systemic vascular disease - Hypertension, diabetes mellitus, cardiovascular disease

  • Blood dyscrasias - Polycythemia vera, lymphoma, leukemia

  • Clotting disorders - Activated protein C resistance, lupus anticoagulant, anticardiolipin antibodies, protein C, protein S, antithrombin III

  • Paraproteinemia and dysproteinemias - Multiple myeloma, cryoglobulinemia

  • Vasculitis - Syphilis, sarcoidosis

  • Autoimmune disease - Systemic lupus erythematosus

  • Oral contraceptive use in women

  • Obstructive sleep apnea - This affects more patients with retinal vein obstruction than other disorders; treatment of the sleep apnea may help prevent central vein obstruction. [12]

  • Other rare associations - Closed-head trauma, optic disc drusen, arteriovenous malformations of retina

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