What is the prognosis of central retinal vein occlusion (CRVO)?

Updated: Apr 18, 2019
  • Author: Lakshmana M Kooragayala, MD; Chief Editor: Douglas R Lazzaro, MD, FAAO, FACS  more...
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Answer

For nonischemic CRVO, complete recovery with good visual recovery occurs only in about 10% of cases. Fifty percent of patients will have 20/200 or worse vision. About one third of patients convert to ischemic CRVO. CVOS noted that, of 547 eyes initially diagnosed to have nonischemic central retinal vein obstructions, 185 (34%) progressed to become ischemic central retinal vein obstructions within 3 years; 15% converted within the first 4 months.

For ischemic CRVO, more than 90% of patients will have 20/200 or worse vision. About 60% of patients develop ocular neovascularization with associated complications. About 10% of patients can develop CRVO or other type of vein occlusions within either the same eye or the contralateral eye within 2 years.

The long-term prognosis of CRVO has significantly improved with new anti-VEGF agents and steroids, maintaining good visual acuity for a long duration in most patients, except those with severe ischemic maculopathy. Development of neovascular complications has also decreased with continued monitoring and anti–VEGF treatment.


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