What is central retinal vein occlusion (CRVO)?

Updated: Apr 18, 2019
  • Author: Lakshmana M Kooragayala, MD; Chief Editor: Douglas R Lazzaro, MD, FAAO, FACS  more...
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Answer

Central retinal vein occlusion (CRVO) is a common retinal vascular disorder. Clinically, CRVO presents with variable visual loss; the fundus may show retinal hemorrhages, dilated tortuous retinal veins, cotton-wool spots, macular edema, and optic disc edema. Note the images below.

Recent onset central retinal vein occlusion, showi Recent onset central retinal vein occlusion, showing extensive hemorrhages in the posterior pole and giving the "blood and thunder appearance."
Peripheral fundus view of the same patient with ce Peripheral fundus view of the same patient with central retinal vein occlusion as in the previous image, showing hemorrhages extending all over the fundus.
Fluorescein angiograph of same patient with centra Fluorescein angiograph of same patient with central retinal vein occlusion as in previous images, showing hypofluorescence due to blockage from hemorrhages in the retina. It is not useful to perform a fluorescein angiogram in acute stages of the disease.
Fundus picture of the same patient with central re Fundus picture of the same patient with central retinal vein occlusion as in previous images, showing resolving neovascularization of the disc and panretinal photocoagulation scars.
Fluorescein angiogram of the same patient with cen Fluorescein angiogram of the same patient with central retinal vein occlusion as in the previous images, taken more than 1 year later, showing persistent cystoid macular edema with good laser spots.

In view of the devastating complications associated with the severe form of CRVO, a number of classifications were described in the literature. All of these classifications take into account the area of retinal capillary nonperfusion and the development of neovascular complications. [1, 2, 3, 4, 5]


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