What is the role of spectral-domain OCT in the workup of central retinal artery occlusion (CRAO)?

Updated: Jun 11, 2019
  • Author: Robert H Graham, MD; Chief Editor: Andrew G Lee, MD  more...
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Spectral-domain optical coherent tomography (OCT) has been proposed as one modality that might be used to diagnose and monitor CRAO. 

In CRAO, there is an observed increase in intensity of inner retinal layers compared with age-matched controls, and it corresponds to the layers supplied by central retinal arteries. Chen et al showed that optical intensity on OCT can be correlated with visual prognosis. [26] Incomplete CRAO shows minimal  retinal architectural disruption and inner layer hyper-reflectivity without retinal edema. Subtotal CRAO demonstrated inner macular thickening and loss of organization of the inner retina, and total CRAO demonstrated marked inner retinal thickening and subfoveal choroidal thinning. [27, 28] In the chronic phase, there is a corresponding thinning of the inner retinal layers.

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