What is the role of fluorescein angiography in the workup of central retinal artery occlusion (CRAO)?

Updated: Jun 11, 2019
  • Author: Robert H Graham, MD; Chief Editor: Andrew G Lee, MD  more...
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Answer

Fluorescein angiography (see list of findings indicating CRAO below) may be a prognostic test. [25] Poor perfusion on fluorescein angiography has been associated with lower vision than exudative and mixed perfusion. [25] This finding does not influence therapy.

  • Normal choroidal filling begins 1-2 seconds before retinal filling and is complete within 5 seconds of dye appearance in healthy eyes. A delay of 5 or more seconds is seen in 10% of patients. Consider ophthalmic artery occlusion or carotid artery obstruction if choroidal filling is significantly delayed.
  • Delay in arteriovenous transit time (reference range, < 11 seconds)
  • Delay in retinal arterial filling
  • Arterial narrowing with normal fluorescein transit after recanalization

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