What is the role of optical coherent tomography angiography (OCTA) in the workup of central retinal artery occlusion (CRAO)?

Updated: Jun 11, 2019
  • Author: Robert H Graham, MD; Chief Editor: Andrew G Lee, MD  more...
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Optical coherent tomography angiography (OCTA) is a novel noninvasive technique that eliminates the need for dye injection to evaluate the retinal microvasculature. It is based on the principle that static and nonstatic structures (ie, blood flowing through vessels) generate different signal amplitudes on repeated B scans from the same cross-sections. OCTA provides structural and functional (blood flow) information at a fixed point; however, it is not useful to appreciate leakage from vessels. [29]

OCTA shows decreased vascular perfusion in superficial and deep retinal plexus that corresponds to poor perfusion on fluorescein angiography. In patients with the cilioretinal artery–sparing variant, the deep capillary plexus retained perfusion. However, unlike fundus fluorescein angiography, OCTA cannot demonstrate a delay in transit time. [30]

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