When is the ACTH stimulation test normal in patients with hypopituitarism (panhypopituitarism)?

Updated: Jun 09, 2020
  • Author: Bernard Corenblum, MD, FRCPC; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Answer

Hypopituitarism may manifest several years after radiation exposure and in chronic Sheehan syndrome. In acute pituitary failure, as in Sheehan syndrome, the ACTH stimulation test may be normal because the adrenal glands are not atrophied in the acute setting, requiring at least 3 months.


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