Which conditions should be included in the differential diagnoses of hypoglycemia (low blood sugar)?

Updated: Jul 23, 2020
  • Author: Osama Hamdy, MD, PhD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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The following should also be considered when evaluating a patient with hypoglycemia:

  • Hepatic disease: (eg, hepatic failure, cirrhosis, galactose intolerance, fructose intolerance, glycogen storage diseases) [20]

  • Transient ischemic attacks

  • Cardiac dysrhythmia

  • Endocrine disorders (eg, pheochromocytoma, Addison disease, glucagon deficiency, carcinomas, extrahepatic tumors)

  • Substance abuse (eg, cocaine, ethanol, salicylates, beta-blockers, pentamidine)

  • Hypoglycemic agents (eg, insulin, oral hypoglycemic agents)

  • Nutritional disorders (eg, prolonged starvation before anesthesia, protein calorie malnutrition, L-leucine-sensitive hypoglycemic defect in children, low-calorie ketogenic diet, renal disease)

  • Autoimmune disorders (eg, Graves disease)

  • Central nervous system (CNS) disorders

  • Psychogenic

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