What is the role of lab studies in the diagnosis of hypoglycemia (low blood sugar)?

Updated: Sep 12, 2019
  • Author: Osama Hamdy, MD, PhD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Answer

Patients with no previous history of hypoglycemia require a complete workup to find a potentially treatable disease. Laboratory studies that should be obtained include the following:

  • Glucose and electrolyte levels (including calcium, magnesium)

  • Oral glucose tolerance test and/or 72-hour fasting plasma glucose

  • Complete blood count

Other tests that may be helpful including the following:

  • Blood cultures

  • Urinalysis

  • Serum insulin, cortisol levels, and thyroid hormone levels

  • C-peptide levels

  • Proinsulin


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