How is fungal keratitis in HIV infection treated?

Updated: Jul 21, 2021
  • Author: Luca Rosignoli, MD; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Answer

Answer

Initially, corneal infiltrates and ulcers are usually treated as bacterial infections until the results of cultures and/or staining are obtained. If cultures indicate fungal keratitis, then treatment with topical natamycin 5% (50 mg/mL) and cycloplegic agent should be initiated

For deep stromal infection, combination medication should be considered; options include topical amphotericin B, topical fumagillin, miconazole or clotrimazole and/or oral fluconazoleitraconazole, or albendazole.


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