Which medications in the drug class Topical corticosteroids are used in the treatment of Ophthalmologic Approach to Chemical Burns?

Updated: Oct 08, 2019
  • Author: Mark Ventocilla, OD, FAAO; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Answer

Topical corticosteroids

Steroids decrease ocular surface inflammatory response, facilitating earlier epithelial healing and regeneration. These medications should be tapered after 7-10 days because of the risk of corneal melting with prolonged use. Should inflammation persist, systemic anti-inflammatory agents, including oral steroids (prednisone), should be considered.

Prednisolone acetate 1% (Pred Forte, Econopred)

Decreases corneal inflammation and neovascularization, uveitis, and anterior segment inflammation.

Fluorometholone acetate 0.1% (FML, FML Forte, Flarex)

Decreases corneal inflammation and neovascularization, uveitis, and anterior segment inflammation.

Rimexolone 1% (Vexol)

Decreases corneal inflammation and neovascularization, uveitis, and anterior segment inflammation.

Loteprednol etabonate 0.5% (Lotemax)

Decreases corneal inflammation and neovascularization, uveitis, and anterior segment inflammation. Reduces risk of steroid-induced IOP elevation.

Difluprednate 0.05% (Durezol)

Decreases corneal inflammation and neovascularization, uveitis, and anterior segment inflammation. Considered the strongest topical steroid, contains less toxic preservative sorbitol, and more likely to induce significant IOP elevations than other topical steroids.


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