What is the role of lab tests in the workup of xanthelasma?

Updated: Feb 08, 2021
  • Author: Andrew A Dahl, MD, FACS; Chief Editor: Edsel B Ing, MD, MPH, FRCSC  more...
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Since more than 50% of patients with xanthelasma have lipid disorders, it is recommended that their plasma lipid levels are obtained, including LDL cholesterol and HDL cholesterol levels, triglyceride level, and apolipoprotein B100 level. Xanthelasma are usually an obvious clinical diagnosis, but, in rare cases, other lesions can simulate the appearance and may be associated with disorders of a more serious nature. If there is any doubt, surgical excision and pathologic analysis should be performed.

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