How is the risk for developing CHD determined in patients with familial hypercholesterolemia (FH)?

Updated: Oct 04, 2021
  • Author: Mose July, MD, CCD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Answer

Percent risk for developing CHD or having a major CHD event (ie, fatal or nonfatal myocardial infarction) is determined by calculating the Framingham risk score, which is available through the US National Heart, Lung, and Blood Institute (see Risk Assessment Tool for Estimating 10-Year Risk of Developing Hard CHD).

  • LDLc goal less than 100 mg/dL

  • Therapeutic lifestyle changes (TLC) instituted at LDL 100 mg/dL or more

  • Medical therapy initiated at LDL 100 mg/dL or more (new 2004 cut off point)


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