Which histologic findings are characteristic of dacryocystitis?

Updated: Oct 08, 2019
  • Author: Grant D Gilliland, MD; Chief Editor: Edsel Ing, MD, MPH, FRCSC  more...
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Pathologic changes found in the lacrimal drainage system are related primarily to the etiology of the disease.

Because the most common underlying pathogenic factor is distal obstruction of the lacrimal drainage system with subsequent stagnation and infection, the most common pathologic finding in the lacrimal drainage system is inflammatory change. Chronic inflammation and fibrosis of the lacrimal sac are present in varying degrees in most patients.

Focal ulceration and loss of goblet cells are not uncommon.

Focal abscesses and granuloma formation also have been noted in the lacrimal sac.

The pathologic changes in the nasolacrimal duct and nasal mucosa follow closely to those in the lacrimal sac.

Chronic inflammation and fibrosis are the most common histologic changes noted in both the nasal mucosa and the nasolacrimal duct.

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