What is the prognosis of juvenile xanthogranuloma (JXG)?

Updated: Feb 08, 2019
  • Author: Bhupendra C K Patel, MD, FRCS; Chief Editor: Michael Taravella, MD  more...
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Spontaneous regression of skin lesions is the natural course, but in ocular disease, regression has only been infrequently documented.

JXG is an important cause of spontaneous hyphema in childhood, the sequelae of which include secondary glaucoma and blindness.

Visual prognosis of iris JXG depends upon prompt diagnosis and treatment prior to intraocular hemorrhage. Once hyphema occurs, visual morbidity increases substantially.

In patients with other ocular or orbital involvement, prognosis varies with the extent of the disease and its response to treatment.

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