What anatomy of the eye is relevant to understanding penetrating keratoplasty and glaucoma (PKPG)?

Updated: Dec 30, 2020
  • Author: Shibandri Das, MD; Chief Editor: Inci Irak Dersu, MD, MPH  more...
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Answer

The anterior chamber is considered the "front part" of the eye; this is a fluid-filled space. This anterior chamber is filled with a fluid called aqueous humor, which is constantly made by the ciliary body and drained. This fluid provides nutrition and oxygen to the front part of the eye (cornea). An imbalance of this fluid's production and drainage can lead to high pressure within the eye, which can cause optic nerve damage to the back of the eye, defined as glaucoma. Of note, this eye pressure is unrelated to the body's blood pressure, and eye pressure can be normal even if the blood pressure is high (and vice versa). [31]


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