What is the pathophysiology of penetrating keratoplasty and glaucoma (PKPG)?

Updated: Dec 30, 2020
  • Author: Shibandri Das, MD; Chief Editor: Inci Irak Dersu, MD, MPH  more...
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Answer

The pathophysiology of PKPG has multiple factors; it may be associated with distortion of the angle with collapse of the trabecular meshwork, suturing technique, postoperative inflammation, corticosteroid use, repeat corneal transplant, and/or peripheral anterior synechiae (including history of uveitis). The usual factors that contribute to postoperative glaucoma, such as preexisting glaucoma, postoperative inflammation, use of viscoelastic substances, iatrogenic injury to the angle, and steroid-induced glaucoma, should also be considered. [13]


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